听力检查可能发现自闭症风险

Researchers have identified an inner ear deficiency in children with Autism that may impact their ability to recognize speech. The findings, which were published in the journal Autism Research, could ultimately be used as a way to identify children at risk for the disorder¹ at an early age. "This study identifies a simple, safe, and non-invasive method to screen young children for hearing deficits² that are associated with Autism," said Anne Luebke, Ph.D., an associate professor in the University of Rochester Medical Center Departments of Biomedical Engineering and Neuroscience and a co-author of the study. "This technique may provide clinicians a new window into the disorder and enable us to intervene earlier and help achieve optimal³ outcomes." 

 

Autism Spectrum⁴ Disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social-communication skills and restricted and repetitive behaviors. While many signs of ASD are present before age two, the majority of children with ASD are not diagnosed until after age four, which means that corrective therapies are started later, delaying their potential impact. 

 

One of the challenges to early detection of ASD is to find ways to identify children at risk for the disorder sooner and in children with speech delays. Some of the earliest and consistent signs of ASD involve auditory communication, however, most tests rely on speech, and are often ineffective in children who are very young or who have communication delays.

 

In the new study, researchers used a technique that measures what are called otoacoustic emissions⁶. The test is akin⁷ to the screening that many newborns must undergo before leaving the hospital to check for hearing problems. Using miniature speaker/microphone earplugs, the researchers were able to measure hearing deficiencies by listening for signs that the ear is having difficulty processing sounds. Specifically, the device's highly sensitive microphone can detect minute sound emission⁵ made by inner ear outer hair cells in response to certain tones or clicking sounds. If these cells are not functioning properly, the device fails to detect an emission which indicates that inner ear - or cochlear - function is impaired⁸. 

 

The researchers tested the hearing of children between the ages of 6 and 17, roughly half of whom have been diagnosed with ASD. They found that the children with ASD had hearing difficultly in a specific frequency (1-2 kHz) that is important for processing speech. They also found a correlation⁹ between the degree of cochlear impairment and the severity of ASD symptoms.

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